Further, when normalized to the number of neurons responding to the positive control KCl stimulation, a significantly higher percentage of VSN CART responded to 22.2 mmol/L glucose compared with 2.2 mmol/L glucose, while the response to 4.4 mmol/L glucose showed a trend toward being higher than that observed with 2.2 mmol/L glucose ( Figure 8 B).
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A distinct vagus-beta cell neural circuit senses glucose and modulates insulin secretion.
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