Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis.

Notably, AAV9‐Fntb delivery significantly improved diastolic function in HFD‐fed mice, as evidenced by a normalized E/A ratio (Figure 6k ), and showed a clear trend toward attenuated interstitial fibrosis (Figure 6l ).

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