Intersection of alcohol use, pain symptoms, and negative affect in total knee arthroplasty patients and people with HIV.

In the NOAH cohort, SF-36 pain intensity scores were higher (less pain) for alcohol drinkers (AUDIT-C ≥ 1) compared to non-drinkers (AUDIT-C = 0), although this difference did not reach statistical significance (p=0.648, t=0.4567, df=362, Fig. 1A ); however SF-36 pain interference scores were significantly higher (less pain interference) among alcohol drinkers with AUDIT-C ≥ 1 compared to non-drinkers (p=0.027, t=2.228, degrees of freedom (df)=362, Fig. 1B ).

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