Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.

Ther Clin Risk Manag · 2026 · PMC13159737 · PMID 42125734

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a significant trendno p-value reported

21 , 22 Although esketamine did not demonstrate a statistically significant increase in analgesic efficacy at 24 and 48 hours postoperatively, it showed a significant trend toward lower pain levels compared with magnesium sulfate, suggesting potential clinical significance.

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