Although the results did not reach statistical significance, the increase in DPT cells has been associated with the pathogenesis of various liver diseases ( 38 , 39 ).
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Single-cell CyTOF profiling reveals alterations in B, T and macrophage subsets during murine hepatic aging.
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We further gated pro-B cells, memory B cells, and plasma B cells; however, the numbers of these cells did not increase but instead showed a decreasing trend ( Figures 4c, d ; Supplementary Figure S11 ).