highly significantp < 0.001
The primary outcome, MMSE, showed a highly significant improvement during active intervention periods compared to control periods ( p < 0.001), even after stringent FDR correction.
The primary outcome, MMSE, showed a highly significant improvement during active intervention periods compared to control periods ( p < 0.001), even after stringent FDR correction.
While secondary outcomes, such as DSF, TMT-A/B, and psychosocial scales, exhibited modest improvements, these changes did not reach statistical significance in the GEE model after multiple comparison adjustments ( Table 3 ).