Chronic quercetin supplementation modulates cardiac function and signaling pathways in aged male Wistar rat hearts subjected to ischemia-reperfusion.

Front Cardiovasc Med · 2026 · PMC13160773 · PMID 42131093

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0.0594

closest p · 1.2× alpha

0.0594

boldest claim

The sentences

marginal significanceP = 0.0594so close (0.05 < p ≤ 0.1)

This effect was manifested by a shortening of the QT interval which reached marginal significance ( P = 0.0594) and a tendency toward QTc improvement ( P = 0.0921) compared with the control group at comparable heart rate ( Figure 4 ). 3.3.

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showed a trendno p-value reported

Chronic QCT treatment also showed a trend toward reduced apoptosis induction in left ventricular (LV) heart tissue, as evidenced by an increase in Bcl-2/Bax ratio; but without significant alterations in TNFR1 and caspase-8 expression, as well as no changes in autophagic proteins such as Beclin-1 and the LC3I/LC3II ratio.

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