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Synergistic effect of octenidine gel and hydrogel dressing in the treatment of venous leg ulcers.

Front Pharmacol · 2026 · PMC13160818 · PMID 42131802

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A comprehensive meta-analysis published in 2024, synthesizing data from 18 randomized trials, demonstrated that although silver-containing dressings significantly improved healing rates in diabetic foot ulcers, their effectiveness in VLUs did not reach statistical significance, suggesting limited and inconsistent benefits in this patient population ( Yi et al., 2024 ).

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