Safety and preliminary efficacy of Aurora: a pilot, non-randomized clinical trial of a culturally adapted digital cognitive behavioral therapy intervention for anxiety and depression in Mexico.

In the parsimonious model, Module effect remained highly significant (p<0.001), and Item also showed a significant main effect (p<0.001), indicating different average levels across items but no differences in their pattern of change.

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The association with change in pathological worry approached significance (r = -0.38; p = 0.071), suggesting that increases in positive emotion may preferentially influence cognitive domains characterized by repetitive negative thinking ( 22 ).

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