Effect of Vitamin D Supplementation Regimens on Fracture Healing and Serum Biomarker Profile in Long-Bone Fractures: A Prospective Randomized Study.

Although this difference did not reach statistical significance, likely due to the limited sample size, the observed trend is consistent with the post hoc findings of Slobogean et al., [ 13 ] where high-dose Vitamin D3 supplementation was associated with modest improvements in clinical fracture healing scores compared to placebo at 3 months and over 12 months.

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