Although differences in PFS and OS among other grade comparisons did not reach statistical significance, there was a consistent downward trend in both PFS and OS with increasing IASLC grade (Figure 4 ), suggesting a trend toward poorer prognosis in patients with higher‐grade tumors.
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The prognostic significance of the IASLC grading system in ALK-positive invasive non-mucinous adenocarcinoma of the lung: correlation with clinicopathological features.
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The incidence of distant metastasis showed an increasing trend with higher IASLC grade, and the difference was statistically significant (Figure 3C ; Table 1 ).