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uPAR-Targeting Cytotoxic Antibody-Drug Conjugates Selectively Deplete Proinflammatory Myeloid Cells for Autoimmune Indications.

Cells · 2026 · PMC13162639 · PMID 42121904

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Relative to the isotype control-MMAF, uPAR-MMAF produced a 39% reduction that did not reach statistical significance ( Figure 5 I).

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