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Tumour acquisition method and molecular profiling success in advanced cholangiocarcinoma.

Acta Oncol · 2026 · PMC13162784 · PMID 42093564

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Endoscopic ultrasound fine needle biopsy (EUS-FNB) and surgical/percutaneous biopsies demonstrated superior success rates compared to cytology-based approaches like EUS-fine needle aspiration (EUS-FNA) and biliary brushings, although this did not reach statistical significance, likely due to small sample size in the EUS-FNB group ( Figure 1 ).

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