Optical Coherence Tomography-Guided Versus Angiography-Guided PCI in Moderate-to-Severe Calcified Coronary Lesions: A Systematic Review and Meta-Analysis of Randomized Trials.

Diagnostics (Basel) · 2026 · PMC13163070 · PMID 42122021

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did not reach statistical significanceno p-value reported

The pooled MSA analysis demonstrated a directional benefit favoring OCT guidance; however, the effect did not reach statistical significance under the primary random-effects model and with significant heterogeneity (MD = 0.91; 95% CI: −0.45–2.27; I 2 = 95%).

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