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Analysis of Clinical Impact of CD33 rs12459419 Single-Nucleotide Polymorphism in AML Treated with Intensive Chemotherapy Without Gemtuzumab Ozogamicin.

Int J Mol Sci · 2026 · PMC13163365 · PMID 42123630

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closest p · 2.0× alpha
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showed a trendp = 0.10so close (0.05 < p ≤ 0.1)
In CD33 high patients, there was a trend toward longer OS ( p = 0.23), EFS ( p = 0.10), and RFS ( p = 0.059) in carriers of the T allele, whilst in CD33 low patients, carriers of the T allele showed a trend toward shorter survival (OS: p = 0.10; EFS: p = 0.07; RFS: p = 0.09).

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