The <i>Ganoderma lucidum</i> and <i>Rosa roxburghii</i> Tratt Formulation Prevents Depressive-like Behaviors in Mice by Modulating Tryptophan Metabolism via the Gut-Brain Axis and Upregulating the BDNF/TrkB/PI3K/AKT Pathway.

Foods · 2026 · PMC13163458 · PMID 42121478

Europe PMC DOI

hedged sentence

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closest p · 1.0× alpha

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boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant

The tryptophan metabolism pathway did not reach statistical significance ( p > 0.05).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

The &lt;i&gt;Ganoderma lucidum&lt;/i&gt; and &lt;i&gt;Rosa roxburghii&lt;/i&gt; Tratt Formulation Prevents Depressive-like Behaviors in Mice by Modulating Tryptophan Metabolism via the Gut-Brain Axis and Upregulating the BDNF/TrkB/PI3K/AKT Pathway.

The sentences

The <i>Ganoderma lucidum</i> and <i>Rosa roxburghii</i> Tratt Formulation Prevents Depressive-like Behaviors in Mice by Modulating Tryptophan Metabolism via the Gut-Brain Axis and Upregulating the BDNF/TrkB/PI3K/AKT Pathway.