Prognostic Impact of Carvedilol vs. Metoprolol on Long-Term Outcomes in Patients with Heart Failure and Mildly Reduced Ejection Fraction.

J Clin Med · 2026 · PMC13163702 · PMID 42123080

Europe PMC DOI

hedged sentence

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

did not reach statistical significancep = 0.064so close (0.05 < p ≤ 0.1)

A trend toward improved survival with higher dose categories was noted for the secondary endpoint; however, this did not reach statistical significance (log-rank p = 0.064).

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