Baseline demographic characteristics were broadly similar between the two groups; however, postoperative adjuvant therapy was more frequent in the vNOTES group, and pathological upstaging was numerically more frequent in the vNOTES group, although the difference did not reach statistical significance.
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Mid-Term Oncological Outcomes of Vaginal Natural Orifice Transluminal Endoscopic Surgery Compared with Total Laparoscopic Hysterectomy for Early-Stage Endometrial Cancer: A Single-Center Retrospective Study.
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On multivariable Cox proportional hazards regression analysis, lymphovascular space invasion was the only significant prognostic factor for RFS, whereas pathological upstaging showed a nonsignificant trend ( Table 3 ).