Impact of Pharmacogenetic Markers on the Efficacy of Neoadjuvant FLOT Chemotherapy in Patients with Gastric and Gastroesophageal Junction Adenocarcinoma.

Int J Mol Sci · 2026 · PMC13164360 · PMID 42123691

Europe PMC DOI

hedged sentences

0.1080

closest p · 2.2× alpha

0.1080

boldest claim

The sentences

did not reach statistical significancep = 0.108not close (p > 0.1)

Although a trend toward a more favorable prognosis was observed in patients with a pronounced pathological response, the differences between groups, assessed using the likelihood ratio test, did not reach statistical significance ( p = 0.108).

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an expected trendno p-value reported

Analysis of progression-free survival showed an expected trend toward improved outcomes in patients with a favorable pathological response (TRG0–2); however, the differences did not reach statistical significance ( p = 0.108).

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