Barely Significant
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The non-steroidal mineralocorticoid receptor blocker esaxerenone reduces glomerular hyperfiltration and albuminuria.

Nephrol Dial Transplant · 2026 · PMC13165900 · PMID 41206562

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showed a trendno p-value reported
The afferent:efferent arteriole ratio (AA:EA) showed a trend toward an increase in the aldosterone-treated group compared with the control group, but this difference was not statistically significant.

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