The role of circulating cytokines in eosinophilic esophagitis: A Mendelian randomization and gene expression analysis study.

Medicine (Baltimore) · 2026 · PMC13166836 · PMID 42116318

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nominally significantno p-value reported

Our MR analysis identified nominally significant associations where genetically predicted higher levels of interleukin-8 (IL-8) and C-C motif chemokine ligand 19 (CCL19) were associated with an increased risk of EoE, whereas higher levels of hepatocyte growth factor were associated with a decreased risk ( P < .05; P _fdr < .2).

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