Barely Significant
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Extended High-Dose Tofacitinib Induction Improves Clinical Response in Ulcerative Colitis: A Multicenter Cohort Study.

JGH Open · 2026 · PMC13167392 · PMID 42136912

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hedged sentence
0.2500
closest p · 5.0× alpha
0.2500
boldest claim

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did not reach statistical significancep = 0.25not close (p > 0.1)
Although clinical remission rates were also higher with extended induction, this difference did not reach statistical significance at week 16 (55% vs. 44%, p = 0.25) or 52 (67% vs. 53%, p = 0.22) (Figure 2 ).

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