Differential expression of GLP1R, PCSK9, and SGLT2 in human aortic versus mitral valve tissues: exploratory findings in calcific aortic valve disease.

Comparison of target expression between calcified and non-calcified tissues Within the AV group, GLP1R, PCSK9, and SGLT2 expression levels showed a higher expression trend in the calcified tissues compared with non-calcified tissues; however, these differences did not reach statistical significance ( P > 0.05) ( Table 3 ; Figure 2 ), possible due to limited sample size.

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