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The association between skeletal muscle-to-fat mass ratio and insulin resistance in obese children with low skeletal muscle mass.

BMC Endocr Disord · 2026 · PMC13169554 · PMID 41928181

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As a partial approach, we performed age-stratified sensitivity analyses using chronological age categories (6–9, 10–13, and 14–17 years) as a proxy for pubertal maturation, and the inverse association between MFR and abnormal insulin resistance remained directionally consistent but did not reach statistical significance after adjustment (Supplementary Table S3 ).

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