Barely Significant
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Systematic review and meta-analysis comparing postoperative and oncological outcomes between local excision plus radiotherapy versus total mesorectal excision for rectal cancer.

World J Surg Oncol · 2026 · PMC13169656 · PMID 41928271

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showed a trendno p-value reported
Additionally, the LE + RT group, although not statistically significant, showed a trend towards higher rates of positive margins and local recurrence in some studies, which should be interpreted with caution.

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