Activation of α7nAChR prevents maladaptive right ventricular remodeling via inhibiting the recruitment of CCR2<sup>+</sup> macrophages in experimental pulmonary arterial hypertension.

Quantitative RT-PCR analysis revealed that RV expression of the chemokine CCL2 and inflammatory cytokines IL-1β and IL-6 showed a trend toward increased expression in the MCT3W group, with a dramatic upregulation observed in the MCT5W group compared with controls (Fig. 2 F).

also in 53,322 other papers

Similarly, RV infiltration of CD43 low His48 high monocytes was markedly reduced in the MCT5W + PNU group compared with the MCT5W + saline group, and there was a decreasing trend compared with the MCT5W + MLA group (Fig. 5 B).

also in 47,180 other papers