Barely Significant
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High Immunohistochemical Expression of Runt-Related Transcription Factor 2 (RUNX2) Is Associated With High Tumor Grade, Muscle Invasion, Lymph Node Metastasis, and Advanced Stage in Urinary Bladder Cancer.

Cureus · 2026 · PMC13170924 · PMID 42137676

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did not reach statistical significancep = 0.749not close (p > 0.1)
a positive trendno p-value reported
An interesting finding revealed in this study was a positive trend toward an association of high immunohistochemical expression of RUNX2 with larger tumor sizes; however, this did not reach statistical significance (p = 0.749) (Table 2 ).

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