Superior long-term survival with acceptable safety of ATG/G-CSF-based haplo-HSCT with intensified BU+MEL/TT conditioning in CR Pediatric Non-DS-AMKL.

Front Oncol · 2026 · PMC13171348 · PMID 42147227

Europe PMC DOI

hedged sentences

0.0880

closest p · 1.8× alpha

0.0880

boldest claim

The sentences

a nonsignificant trendP = 0.088so close (0.05 < p ≤ 0.1)

For severe cGVHD, the MEL/TT+BU regimen showed a nonsignificant trend toward increased risk in univariable analysis (HR 2.97, 95% CI 0.85–10.39, P = 0.088), which was not retained after adjustment (HR 2.28, 95% CI 0.51–10.29, P = 0.280).

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did not reach statistical significanceno p-value reported

30%, P = 0.276), these differences did not reach statistical significance, likely due to limited sample size.

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