Optimising antidepressant therapy in pregnancy: a perspective on therapeutic drug monitoring and model-informed precision dosing.

Looking at the three most commonly prescribed SSRIs, sertraline, fluoxetine, and citalopram, median doses stayed consistent from first through third trimester ( Figure 2 ); though visual inspection suggested a modest upward trend for sertraline that did not reach statistical significance; only 20.4% of cases involved any dose adjustment.

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