Sequential sequencing reveals the architecture and complexity of genomic variants in patients with Alport syndrome.

Nat Commun · 2026 · PMC13171879 · PMID 41872207

Europe PMC DOI

hedged sentence

0.2100

closest p · 4.2× alpha

0.2100

boldest claim

The sentences

did not reach statistical significanceP = 0.21not close (p > 0.1)

Among ARAS patients, an increasing burden of severe variants was associated with a graded elevation in ESKD risk, although this trend did not reach statistical significance ( P = 0.21).

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