Assessment of Guideline-Directed Medical Therapy Optimization Scores and Readmission Risk in Heart Failure With Reduced Ejection Fraction.

Ann Pharmacother · 2026 · PMC13172379 · PMID 41235598

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did not reach statistical significanceno p-value reported

The GDMT count scores for dual (HR: 0.91, 95% CI: 0.55-1.48), triple (HR: 0.78, 95% CI: 0.46-1.34), and quadruple therapy (HR: 0.61, 95% CI: 0.35-1.06) did not reach statistical significance, despite showing a trend toward benefit with increasing the number of agents at discharge ( Figure 4 ).

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