Validation of circulating miR-323a-3p and miR-625-3p to classify hypertrophic cardiomyopathy in Friedreich's ataxia.

Sci Rep · 2026 · PMC13172478 · PMID 42128889

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)

Sqrt(miR-323a-3p) showed a positive association with cardiomyopathy (β = 2.255), suggesting that higher values may be associated with increased risk, though this strong trend did not reach statistical significance ( p = 0.053).

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