Bifidobacterium-driven immunoglobulin A production in pediatric patients with IgA deficiency and recurrent respiratory tract infections.

Microbiome · 2026 · PMC13173950 · PMID 42129858

Europe PMC DOI

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0.1600

closest p · 3.2× alpha

0.1600

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The sentences

did not reach statistical significancep = 0.16not close (p > 0.1)

When applying the Canberra distance, which emphasizes low-abundance taxa, the explained variance was reduced and did not reach statistical significance (PERMANOVA R 2 1.4%, p = 0.16 and R 2 1.5%, p = 0.21, respectively), indicating that the observed differences are primarily driven by more abundant taxa.

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