Identification of CAND1 as a DNA-dependent protein kinase-regulated coactivator of androgen receptor and the ARv7 splice variant.

PLoS One · 2026 · PMC13175348 · PMID 42133602

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showed a trendno p-value reported

While the combination was well tolerated, CC-115 was insufficient to inhibit DNA-PK but showed a trend to decreased PSA response in patients with PI3 kinase alternations.

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