Development of an online prediction tool for immunotherapy-related adverse events in patients with advanced NSCLC based on machine learning and temporal validation.

However, in contrast to Michailidou’s report that higher baseline platelet counts (> 145 k/ul) and monocyte count (> 0.29 k/ul) increase the risk of irAEs, this study found that lower baseline platelet count and neutrophil count were significantly tied to irAEs in univariate analysis of both the total development set and training set, whereas monocyte count did not reach statistical significance (P = 0.082 and P = 0.128, respectively).

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