Apoptosis and Glial Marker Profiles in Hippocampus and Amygdala of Medically Intractable Temporal Lobe Epilepsy.

J Cell Mol Med · 2026 · PMC13175923 · PMID 42135614

Europe PMC DOI

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0.0800

closest p · 1.6× alpha

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The sentences

a negative trendp = 0.08so close (0.05 < p ≤ 0.1)

In epileptic patients, hippocampal IBA1 expression showed a negative trend with age ( r = −0.48, p = 0.08), and a similar inverse trend was observed between amygdala caspase‐12 expression and age ( r = −0.48, p = 0.08; Figure 4B ).

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a positive trendp = 0.08so close (0.05 < p ≤ 0.1)

In addition, a positive trend between hippocampal caspase‐12 and caspase‐9 expression was observed in controls ( r = 0.61, p = 0.08; Figure 4A ).

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a possible trendno p-value reported

Positive, non‐significant correlations between caspase‐12 and caspase‐9 in the hippocampus, and between caspase‐9 and caspase‐3 in the amygdala, suggest a possible trend toward coordinated activation of the intrinsic apoptotic cascade.

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