LOX Inhibition Disrupts a Collagen-Integrin-MYC Axis to Suppress Progression of Invasive Lobular Carcinoma.

Cancer Res · 2026 · PMC13176829 · PMID 41706704

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

failed to reach significanceP = 0.08so close (0.05 < p ≤ 0.1)

The effect on the mammary tumors failed to reach significance ( P = 0.08; Fig. 3H ) but ex vivo radiance in the lungs, which was well above background levels in the lungs of control mice, was reduced in the treated animals ( Fig. 3I ).

also in 4,113 other papers

showed a trendno p-value reported

When cells cultured under stiff (4 mg/mL) conditions were treated with PXS-5505 for 7 days, transcript expression of JUN and FOS was significantly decreased, whereas CCN1 and MYC showed a trend ( Fig. 7G ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.