Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens.

J Anim Sci Biotechnol · 2026 · PMC13177867 · PMID 42135842

Europe PMC DOI

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did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

Among males, on d 10 in the 20 μg TeBi1 trial, the treatment group had an approximately 2.8% lower CV compared to the control group, but this difference did not reach statistical significance ( P = 0.07) (Fig.

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a slight trendP = 0.1so close (0.05 < p ≤ 0.1)

S4), but for TeRu4-treated birds on d 4, there was a slight but similar trend of decreased numbers of infected birds with increasing AMP dose (air sac: P = 0.009, pericardium: P = 0.1), and for PeNi4, on d 4, in the air sac only, there was a slight trend of increasing numbers of infected birds with increased AMP dose ( P = 0.1).

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