An HHEX/IKKα positive feedback loop promotes intestinal inflammation.

J Clin Invest · 2026 · PMC13178647 · PMID 41842946

Europe PMC DOI

hedged sentence

0.0666

closest p · 1.3× alpha

0.0666

boldest claim

The sentences

did not reach statistical significanceP = 0.0666so close (0.05 < p ≤ 0.1)

Additionally, a positive correlation was observed between cytoplasmic HHEX expression in IECs and pathological score across 15 UC samples ( R = 0.5585, P = 0.0319), whereas correlation between nuclear HHEX expression in IECs and pathological score did not reach statistical significance ( R = 0.4919, P = 0.0666) ( Figure 1E ).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.