Modulation of WNT and FGF18 enhances yield and subtype identity of hPSC-derived midbrain dopamine neurons.

J Clin Invest · 2026 · PMC13178649 · PMID 42138078

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Basal membrane properties of mDA neurons (Boost+ versus Boost) by patch-clamp recording on day 60 showed no major differences, though Boost+ mDA neurons showed a trend toward lower input resistance, higher cell capacitance, and an increased spontaneous action potential (sAP) frequency ( Figure 2, C–F ).

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