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The atypical E3 ligase HOIL-1 safeguards the ribosome during cellular stress.

Nat Cell Biol · 2026 · PMC13179138 · PMID 42062483

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LV contractile function, as assessed by LV ejection fraction, trended lower in male HOIL-1 ΔRBR mice than WT mice but did not reach statistical significance by 8 weeks (Fig. 1i ).

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