Effect of probiotics derivatives (postbiotics and metabiotics) on glycemic control in individuals with type 2 diabetes: a randomized clinical trial (DELI_Diab study).

The primary analysis using repeated-measures ANOVA demonstrated a highly significant overall treatment effect for HbA1c (p<0.001), indicating distinct patterns of glycemic changes between the groups.

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Notably, while within-group improvements in %B ( Figure 3 ) and BMI ( Figure 4 ) were observed in the Del-Immune group (p<0.05), these did not reach statistical significance when compared directly to the placebo group.

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