Although quantitative analysis of the Dysf Δ5/Δ5 signal did not reach statistical significance, a noticeable trend toward increased intensity was observed in Dysf Δ5/Δ5 mice compared to WT controls (WT, n = 3; Dysf Δ5/Δ5 , n = 3; p = 0.1) (Fig. 4 C).
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Generation of a novel Dysferlin microdeletion knock-in mouse model mimicking muscular dystrophy-like pathology.
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