Conversely, an increasing trend was observed for patients with congenital GHD, but the sample size for this group of patients was limited (n = 18), and statistically significance was not reached ( P = .336, test for interaction).
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GH Response to Glucagon in Transition: Role of Body Mass Index and Etiology in Childhood-onset GH Deficiency.
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Specifically, group differences remained significant, whereas the effect of BMI SDS did not reach statistical significance, suggesting that hypothalamic-pituitary damage, rather than adiposity, was the predominant determinant of GH response.