Lactate dehydrogenase-to-albumin ratio predicts 30-day and 90-day mortality in glucocorticoid-treated ICU patients with pneumonia: a secondary analysis of a multicenter cohort.

Notably, in Model 4, which replaced the PSI score with the CURB-65 score, the prognostic value of LAR remained highly significant and the effect estimates remained stable (30-day HR = 2.52, 95% CI: 1.51–4.21, p < 0.001; 90-day HR = 2.55, 95% CI: 1.59–4.08, p < 0.001), indicating that the independent predictive ability of LAR is robust to the specific disease severity score employed for adjustment.

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The addition of LAR to the CURB-65 score showed a directionally positive improvement, although it did not reach statistical significance.

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