Glucocorticoids induce a phagocytic C1Q+ macrophage phenotype primed for IFNγ-dependent CXCL9 secretion.

Sci Rep · 2026 · PMC13183869 · PMID 42151378

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a notable trendno p-value reported

Although not statistically significant, we observed a notable trend towards an increase in M1-like macrophage polarization (CD11b+ F4/80 + CD11c+) in the ICI+MIFE group compared to the ICI monotherapy group (Fig. 5 D).

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did not reach statistical significanceno p-value reported

In addition, most of the mouse experiments did not reach statistical significance, likely due to the limited number of animals included.

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