Fetal brain volumes and brain gyrification index associated with opioid exposure.

Brain Commun · 2026 · PMC13184692 · PMID 42164953

Europe PMC DOI

hedged sentence

0.0675

closest p · 1.4× alpha

0.0675

boldest claim

The sentences

did not reach statistical significanceP = 0.0675so close (0.05 < p ≤ 0.1)

There was a trend towards a larger difference in gyrification indices between the opioid-exposed and unexposed fetuses with increasing gestational age; however, this did not reach statistical significance ( P = 0.0675, Fig. 3 ).

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