Compared with the placebo, the 400-mg dose administered on days 0 and 90 produced a significant reduction in ApoB on day 180 (−14.3%, P = 0.0085), whereas the effects of the 100- and 800-mg doses did not reach statistical significance.
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RNA-Targeted Therapeutics for Lipid Metabolic Disorders: From Bench to Bedside.
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