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From dysbiosis to decolonization: The emerging role of fecal microbiota transplantation in antimicrobial resistance.

Infect Med (Beijing) · 2026 · PMC13185979 · PMID 42164024

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7 Although all FMT recipients remained culture-positive for at least one MDRO at follow-up (reflecting the difficulty of achieving complete eradication in this setting), exploratory analyses suggested potential clinical benefits: No FMT recipients developed positive blood cultures in the six months after treatment, compared with 19% of controls, and FMT recipients had numerically fewer days of antibiotic therapy per 1000 patient-days, although these differences did not reach statistical significance in this small pilot. 7 The Sentinel REACT data also illustrated that even when MDRO cultures remain positive, FMT can increase microbial diversity and reduce intestinal pathogen dominance, which has been linked in other studies to lower risks of bloodstream and urinary infections. 7 Species-level a

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