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The resistance landscape of EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer: molecular mechanisms and novel therapeutic strategies.

Transl Lung Cancer Res · 2026 · PMC13186667 · PMID 42170254

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Although OS benefits were observed in the two clinical trials, extended follow-up data from NEJ009 revealed that this OS advantage did not reach statistical significance ( 181 ).

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